An antibody locking onto a single target
Research and Development

Stealth-Body, a delivery vehicle
that goes only where it is aimed

Approach & Strategy

Stealth-Body

Proprietary Fc mutations that switch off effector function while leaving antigen binding intact.

Across the Fc gamma receptor panel, it shows no binding and no effector activity above background.

Effector engagement is one way an antibody acts on tissue it was never aimed at. Closing that route matters most when the antibody is carrying a payload.

Because the silenced Fc works the same whatever it carries, one architecture serves small molecules, nucleic acids and proteins alike.

Mechanism

Wild-type Fc vs Stealth-Body

18 sec · Wild-type Fc antibodies bind immune cells; Stealth-Body passes them by and reaches disease cells.

Delivery modalities

Protein, small molecule, nucleic acid

A Stealth-Body antibody surrounded by the payload classes it carries: an oligonucleotide, a small molecule, a lipid nanoparticle and a protein
Pipeline

Development stage

Contact

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